Development and validation of analytical method for metabolomic and peptidomic analysis Line of research Metabolomic and peptidomic study for characterization of new compounds, such as peptides and small molecules. Metabolomic study are carried out on vegetable samples in order to characterize untargeted profiling of biological samples. Staff Supervisor: Anna Laura CapriottiDepartment staff: Chiara CavalierePatrizia FogliaSusy PiovesanaCarmela Maria Montone Publications Peptidomic strategy for purification and identification of potential ACE-inhibitory and antioxidant peptides in tetradesmus obliquus microalgaeChromatographic column evaluation for the untargeted profiling of glucosinolates in cauliflower by means of ultra-high performance liquid chromatography coupled to high resolution mass spectrometryComprehensive polyphenol profiling of a strawberry extract (Fragaria × ananassa) by ultra-high-performance liquid chromatography coupled with high-resolution mass spectrometryCharacterization of antioxidant and angiotensin-converting enzyme inhibitory peptides derived from cauliflower by-products by multidimensional liquid chromatography and bioinformaticsPurification and identification of endogenous antioxidant and ACE-inhibitory peptides from donkey milk by multidimensional liquid chromatography and nanoHPLC-high resolution mass spectrometryEvaluation of column length and particle size effect on the untargeted profiling of a phytochemical mixture by using UHPLC coupled to high‐resolution mass spectrometry Fundings and awards Fundings: PRIN 2015: Securing and ensuring sustainable use of agriculture waste, co- and by-products: an integrated analytical approach combining mass spectrometry with health effect-based biosensingRegione Lazio POR_PNR2017-2020 (Alghe) Bioraffineria integrata per la produzione di biodiesel da microalghe – ORIGAMI. Ricerca Scientifica Sapienza 2016, finanziamento per l’acquisizione di Medie Attrezzature Scientifiche: Valuable products from agro-food industry waste: isolation of bioactive peptides on laboratory preparative scale by means bidimensional chromatograAwards: Premio Giovane Ricercatore Chimica Analitica consegnato in occasione del XXVI Congresso Nazionale della Società Chimica Italiana, Paestum (Piovesana)Premio Genzo Shimadzu Oral Award per la migliore comunicazione orale al 40th International Symposium on Capillary Chromatography (ISCC) and 13th GCxGC Symposium (GCxGC) (Piovesana) Theme and ERC Theme: Life-Sciences chemistryERC: LS2_4 MetabolomicsLS9_6 Food sciencesPE4_5 Analytical chemistry
