Development and validation of analytical method for metabolomic and peptidomic analysis Line of research Metabolomic and peptidomic study for characterization of new compounds, such as peptides and small molecules. Metabolomic study are carried out on vegetable samples in order to characterize untargeted profiling of biological samples. Staff Supervisor: Anna Laura CapriottiDepartment staff: Chiara CavaliereSusy PiovesanaCarmela Maria MontoneUniversity staff: Federico Marini Publications Peptidomic strategy for purification and identification of potential ACE-inhibitory and antioxidant peptides in tetradesmus obliquus microalgaeChromatographic column evaluation for the untargeted profiling of glucosinolates in cauliflower by means of ultra-high performance liquid chromatography coupled to high resolution mass spectrometryComprehensive polyphenol profiling of a strawberry extract (Fragaria × ananassa) by ultra-high-performance liquid chromatography coupled with high-resolution mass spectrometryCharacterization of antioxidant and angiotensin-converting enzyme inhibitory peptides derived from cauliflower by-products by multidimensional liquid chromatography and bioinformaticsPurification and identification of endogenous antioxidant and ACE-inhibitory peptides from donkey milk by multidimensional liquid chromatography and nanoHPLC-high resolution mass spectrometryEvaluation of column length and particle size effect on the untargeted profiling of a phytochemical mixture by using UHPLC coupled to high‐resolution mass spectrometry Fundings and awards Fundings: PE6. Diagnostica e terapie innovative nella medicina di precisione. PE0000019 "HEAL ITALIA"PRIN2017 Project “Cutting Edge Analytical Chemistry Methodologies and Bio-Tools to Boost Precision Medicine in Hormone-Related Diseases” 136.877 EUROS- 2018-2023 2017Y2PAB8Progetto di Ricerca scientifica 2018 “Development of innovative and high performant analytical methods based on metabolomics and lipidomics for identification of new biomarkers in gut microbiota” 31.000 EUROS 2018-2022Progetto AGER – seconda edizione (2016) “Valorization of Italian OLive products through INnovative analytical tools – VIOLIN”. 1.000.008 EUROS (120.000 EUROS Capriotti’s unity budget) 2016-2020 20160169PRIN2015 Project “Multifunctional nanotools for advanced cancer diagnostics” 312.119 EUROS (46.284 EUROS Capriotti’s unity budget) 2016-2019 2015TWP83ZAwards: 2018: EuCheMS Lecture Award 2017 by European Chemical Society2015: Young research award by the Analytical Chemistry Division of the Italian Chemical Society Theme and ERC Theme: Life-Sciences chemistryERC: LS2_4 MetabolomicsLS9_6 Food sciencesPE4_5 Analytical chemistry
