Dipartimento di Chimica

Chirality in Plasmonic Nanoparticles and Nanostructures

di Luis M. Liz-Marzán, CIC biomaGUNE (BRTA) and CIBER-BBN, Donostia-San Sebastián, Spain

 

Il seminario si terrà mercoledì 25 ottobre, ore 16, in Aula La Ginestra, Ed. Cannizzaro (CU014).

Abstract

The field of chirality has seen a strong rejuvenation due to the observation of nanoscale chirality in plasmonic nanoparticles. This lecture will highlight recent advances in the field of plasmonic chirality, including novel methods for the synthesis of optically active plasmonic nanomaterials. The focus will be first directed toward chiral nanostructures formed using biological templates, proteins in particular. After demonstration of the directed self-assembly of gold nanorods on amyloid fibers, as well as the mechanistic understanding of chirality at the nanoscale, a potential application for such nanomaterials will be presented. We propose that plasmon-enhanced chiral signals have great potential for use in the detection and therapy of neurodegenerative disorders.¹

The second part of the lecture will deal with the seeded-growth of chiral features on colloidal nanoparticles. This effect can be achieved by using either thiolated amino acids² or chiral co-surfactants,^3,4 through distinct mechanisms, which can be manipulated to obtain nanoparticles with different chiral features and significant optical activity, which can be tuned through the visible and the near IR.

References

1. J. Kumar, H. Eraña, E. López-Martínez, N. Claes, V.F. Martín, D.M. Solís, S. Bals, A.L. Cortajarena, J. Castilla, L.M. Liz-Marzán, Detection of Amyloid Fibrils in Parkinson's Disease Using Plasmonic Chirality, Proc. Natl. Acad. Sci. USA 2018,  115, 3225-3230.

2. B. Ni, M. Mychinko, S. Gómez-Graña, J. Morales-Vidal, M. Obelleiro-Liz, G. González-Rubio, W. Heyvaert, W. Albrecht, J.M. Taboada, F. Obelleiro, D. Vila-Liarte, X. Zhuo, J. Pérez-Juste, I. Pastoriza-Santos, N. López, H. Cölfen, S. Bals, L.M. Liz-Marzán, Chiral Seeded Growth of Au Nanorods into 4-Fold Twisted Nanoparticles with Plasmonic Optical Activity, Adv. Mater. 2023, 35, 2208299.

3. G. González-Rubio, J. Mosquera, V. Kumar, A. Pedrazo-Tardajos, P. Llombart, D. M. Solís, I. Lobato, E. G. Noya, A. Guerrero-Martínez, J. M. Taboada, F. Obelleiro, L. G. MacDowell, S. Bals, L. M. Liz-Marzán, Micelle-Directed Chiral Seeded Growth on Anisotropic Gold Nanocrystals, Science 2020, 368, 1472-1477.

4. X. Zhuo, M. Mychinko, W. Heyvaert, D. Larios, M. Obelleiro-Liz, J.M. Taboada, S. Bals, L.M. Liz-Marzán, Morphological and Optical Transitions during Micelle-Seeded Chiral Growth on Gold Nanorods. ACS Nano 2022, 16, 19281-19292.

 

 Prof. Luis Liz-Marzán - Biosketch

Luis Liz-Marzán is an Ikerbasque Professor at CIC biomaGUNE, in San Sebastián (Spain), where he also served as Scientific Director from 2012 to 2020. Prof. Liz-Marzán graduated in chemistry from the University of Santiago de Compostela (Spain), was postdoc at Utrecht University (The Netherlands) and then Professor at the University of Vigo (1995–2012), where he currently holds a part-time position as Chair of Physical Chemistry. He additionally holds an Honorary Chair at Soochow University. He has also been visiting professor at various research institutions worldwide (USA, Europe, China, Australia) and received numerous scientific awards and honors, including the ACS Nano and Langmuir Lectureship Awards, European Colloid and Interface Society Rhodia Prize, Jaime I Prize on Basic Sciences, Spanish National Award on Chemical Science and Technology, and Lilly Foundation Award on Preclinical Biomedical Research, among others. He is also a member of the Spanish Royal Academy of Sciences, European Academy of Sciences, Academia Europaea and National Academy of Engineering (USA). He currently serves as an executive editor at ACS Nano, and on the editorial advisory board of several journals including Science. Prof. Liz-Marzán has co-authored more than 550 publications in major journals, being named Highly Cited Researcher every year since 2014. He is considered as one of the pioneers in the colloidal synthesis and self-assembly of metal nanocrystals, as well as the characterization and application of their plasmonic properties. More recently, his research has broadened into the biomedical applications of plasmonic nanostructures.