Dipartimento di Chimica

Patrizia Gentili è lieta di invitarvi al seminario: 

Synergistic Molecule Design and Applications: Harmonizing (3P) Peptides, Phosphazenes, and Polymers

di Eray Çalişkan, Bingöl University, Turchia

Il seminario si terrà giovedì 29 maggio 2025, ore 12:00, in Aula Parravano (edificio CU014).

Abstract

This seminar presents an integrated research approach at the intersection of organic, inorganic, and polymer chemistry, centered on developing multifunctional molecules with biomedical and materials-oriented applications. Emphasis is placed on three core areas: the synthesis of amino acid–chalcone conjugates exhibiting selective glutathione S-transferase inhibition and cytotoxic activity; the design of cyclotriphosphazene-based hybrid structures functionalized with peptides or chromophores for enhanced optical, thermal, and biological properties; and the modification of methacrylate- and acrylamide-based polymers through bio-relevant motifs to tailor their dielectric and thermal behavior. Key synthetic methodologies, spectroscopic characterizations, and structure–activity insights will be discussed, highlighting the translational relevance of these systems in both therapeutic and advanced material contexts.

 

Prof. Eray Çalışkan

 

Dr. Eray Çalışkan is an Associate Professor in the Department of Chemistry at Bingöl University.  His research bridges organic, inorganic, and polymer chemistry, with a particular focus on designing multifunctional molecules for biomedical and materials applications. His work spans:

• Phosphazene–peptide conjugates for anticancer activity and molecular docking;
• Amino acid/peptide-based chromophore conjugates (chalcone, coumarin, cinnamoyl) studied for cytotoxicity and genotoxicity;
• Click chemistry-modified functional polymers, including tyrosine-coumarin and ferrocene derivatives for advanced materials;

In 2010, Dr. Çalışkan was awarded a prestigious Ministry of National Education Scholarship from Türkiye to pursue graduate studies abroad. He earned his M.S. in Chemistry at the University of Florida, where he served for three years as a research assistant in the group of Prof. Alan Roy Katritzky, contributing to heterocyclic synthesis and peptide chemistry. 

He completed his Ph.D. at Bingöl University in 2020, with a dissertation focused on chromophore-labeled amino acid conjugates and their dielectric properties. He has led and participated in multiple research projects funded by TÜBİTAK and university grants, and has published in journals including ACS Omega, ChemMedChem, Polyhedron, and Bioorganic Chemistry.

Dr. Çalışkan is also an experienced educator, teaching General and Organic Chemistry, as well as graduate courses such as Stereochemistry, Organic Reaction Mechanisms, and Pericyclic Reactions. He is actively involved in mentoring undergraduate students, many of whom contribute to his research in synthesis of functional polymers and peptide conjugates.