Molecules from biological precursors for the preparation of nanostructured biomaterials: synthesis, self-assembly, applications Line of research Supramolecular structures formed by natural amphiphilic molecules find applications in both biomedical (drug delivery, tissue engineering) and technological (optoelectronics, nanomaterials) fields of nanoscience. The objective of this investigation is the synthesis of amphiphilic molecules starting from biological precursors such as amino acids, sugars and bile salts, and the study of their self-assembly and applications. Ricerca.pdf Staff Supervisor: Luciano GalantiniDepartment staff: Mauro GiustiniAndrea D'AnnibaleUniversity staff: Emilia Severoni Publications “Incorporation of the bacterial reaction centre into dendrimersomes” M. Giustini, C. Bellinazzo, L. Galantini, A. Mallardi, G. Palazzo, S. Sennato, F. Bordi, K. Rissanen Colloids and Surfaces A: Physicochem. Eng. Aspects 2012, 413, 38–43.“Amino acid–bile acid based molecules: extremely narrow surfactant nanotubes formed by a phenylalanine-substituted cholic acid” L. Travaglini, A. D’Annibale, K. Schillén, U. Olsson, S. Sennato, N. V. Pavel, L. Galantini Chem. Commun. 2012, 48, 12011.“Drug-loaded nanoparticles and supramolecular nanotubes formed from a volatile microemulsion with bile salt derivatives” K. M.-Goshen, M. C. di Gregorio, D. Danino, V. H. Soto, S. Magdassi, L. Galantini et al. Phys. Chem. Chem. Phys. 2013, 15, 6016“23Na and 35/37Cl as NMR probes of growth and shape of sodium taurodeoxycholate micellar aggregates in the presence of NaCl” F. Asaro, L. Feruglio, L. Galantini, A. Nardelli Journal of Colloid and Interface Science 2013, 392, 281–287“Catanionic Gels Based on Cholic Acid Derivatives” M. C. di Gregorio, N. V. Pavel, J. Miragaya, A. Jover, F. Meijide, J. Vázquez Tato, V. H. Soto Tellini, Luciano Galantini Langmuir 2013, 29, 12342−12351“pH sensitive tubules of a bile acid derivative: a tubule opening by release of wall leaves” M. C. di Gregorio, N. V. Pavel, F. Meijide, J. Vàzquez Tato, O. Regev, Y. Kasavi, K. Schillén, L. Galantini et al. Phys. Chem. Chem. Phys., 2013, 15, 7560. Collaborations National collaborations: Dipartimento di Scienze Chimiche e Farmaceutiche, Università degli Studi di Trieste (Prof F. Asaro)Dipartimento di Chimica, Università degli Studi di Bari (Prof. G. Palazzo)Laboratorio di Nanotecnologie e Nanoscienze della Sapienza (Dr. S. Sennato)CNR Istituto Di Metodologie Chimiche, Area della Ricerca di Roma 1, Italy (Dr. G. Mancini, Dr. C. Bombelli)Dipartimento di Scienze Fisiche e Chimiche, Università degli Studi dell'Aquila, Italy (Dr L. Giansanti)Dipartimento di Chimica 'G. Ciamician', Università di Bologna, Italy (Prof. G. Falini, Dr S. Fermani) International collaborations: Grupo de Quìmica Supramolecular e Fisicoquìmica, Dep. Quimica Fisica, Univ. de Santiago de Compostela, Spain (Prof. J. V. Tato, Prof. A. Jover, Prof. F. Meijide)Division of Physical Chemistry, Lund University, Sweden (Prof. K. Schillen, Prof. U. Olsson, Dr. M. O. Rabasa)Center for Nanoscience and Nanotechnology (Prof. Shlomo Magdassi) Hebrew University of Jerusalem, IsraelDepartment of Chemical Engineering, Ben Gurion University of the Negev (Prof. Oren Regev)Escuela de Quimica, Universidad de Costa Rica (Prof. V. H. Soto Tellini)The Laboratory of Nanostructured Molecular Assemblies, Faculty of Biotechnology and Food Engineering, Technion – Israel Institute of Technology, Haifa, Israel (Prof. D. Danino)Leana Travaglini School of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv, Israel (Prof. Gil Markovich) Fundings and awards Fundings: Sintesi, caratterizzazione ed applicazioni di tensioattivi biocompatibili derivanti da sali biliari (accordo bilaterale Univ. Sapienza-Univ. de Costa Rica)SAXS study of Bile Salt Derivative Aqueous Solutions (E131100452), European Soft Matter Infrastructure project (ESMI)SAXS study of bile salt derivative aqueous solutions (ID 20110157), SAXS study of amino acid-bile acid derivative aqueous solutions (ID 20120367), at MAX-LAB, CALIPSO program Theme and ERC Theme: MaterialsERC: PE4_1 Physical chemistryPE4_4 Surface science and nanostructuresPE5_10 Colloid chemistry Traineeship offer Availability: three positionsCourse of study (advised): ChemistryIndustrial chemistry
