Mauro Giustini

Mauro Giustini (Rome, 25 July 1961) has been a researcher at the Faculty of Science, working at the Department of Chemistry, "La Sapienza" University, Rome, since 1999. After graduating (with honours) in Biological Sciences in 1985, he spent three years as a visiting scientist at the Institut für Polymere of ETH Zurich (CH), in the group of Prof. P.L. Luisi, working on the characterisation of supramolecular aggregates of surfactants in organic solvents and in water, by NMR, IR and fluorescence spectroscopy. In 1995 he obtained his PhD (Physical Chemistry) at the Department of Chemistry of "La Sapienza" with the thesis "Characterization of a quaternary water-in-oil microemulsion and examples of its possible use for the solubilization of nucleic acids". From 1995 to 1999 he was researcher at the Centro Studi Chimico-Fisici sull'Interazione Luce-Materia of the CNR (c/o Department of Chemistry of the University of Bari) dealing with the spectroscopic characterisation (Self-Diffusion NMR and NIR) of surfactant aggregates in different solvents and with the energetics of photo-induced electron transfer reactions in the Reaction Centre protein reconstituted in different biomimetic environments (micelles, inverse micelles, organogels, liposomes, etc.). He is currently involved in the spectroscopic characterisation (UV-Vis spectroscopy; steady-state and time-resolved fluorescence) of supramolecular aggregates formed by surfactants, polymers and dendrimers as nanocompartmentalised systems capable of hosting proteins, oligo- and polynucleotides, drugs and metal complexes. MG is co-author of more than 60 peer-reviewed papers and numerous conference communications. As part of his teaching activities, he supervised two PhD thesis in Chemical Sciences and several dissertations.
Research activity
Scientific area: 
Inorganic chemistry
Research activity: 
Drug-delivery systems based on micellar aggregates that host species that are not covalently bound to their internal apolar domains have several advantages,, such as ease of preparation and a wide range of drugs that can be solubilised. Pluronics are polypropylene (PEO) block copolymers of polyoxyethylene (PPO) arranged in the pattern (PEO)x(PPO)y(PEO)x. One of the characteristics of pluronic polymers is their self-assembly ability: above a defined concentration (cmc) and temperature (cmt), they self-assemble to give core-shell micelles
Available to students: 
During the teaching semester: Thursday 9-11. Any time, by fixing a meeting via email

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