Pluronics based host-guest systems for drug delivery

Line of research
Drug delivery systems based on micellar aggregates hosting guest species non covalently bound to their inner apolar domains present several advantages, such as ease of preparation and a broad range of drugs that can be solubilized. Pluronics are triblock copolimers made of polyoxyethylene (PEO) polypropylene (PPO) units arranged according the motif (PEO)x(PPO)y(PEO)x. One of the main useful characteristic of pluronics is their self-assembly capability: above a well defined concentration (cmc) and temperature (cmt) they self-assemble to form micelles characterized by a core/shell structure.

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