Stereoselective syntheses of natural products and intermediates of dihydrobenzofuran structure and evaluation of their antitumor activity

Line of research
The research is oriented towards the synthesis and elaboration of 2,3-diaryloxiranes, even in enantioenriched form, to obtain polyfunctionalized 2,3-diaryl-2,3-dihydrobenzofurans stereoselectively . The goal is to develop an original and efficient synthesis of natural dimers of Resveratrol, as epsilon Viniferin, Gnetin C, delta Viniferin, possessing numerous biological and pharmacological activities, in particular anticancer one, together with testing the activity of novel dihydrobenzofuryl intermediates.

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