Enzymatic synthesis of bioactive compounds Line of research Cyclobutanols are present in many natural products and are used as chiral intermediates in total synthesis. However, there are few reactions that allow them to be obtained with high enantiomeric excesses. The aim of this research line is, therefore, the synthesis of 2- (hydroxyimino) aldehydes and the development of an asymmetric version of Norrish-Yang photocycling in order to obtain chiral cyclobutanol oximes. Sintesi di intermedi chirali.pdf Staff Supervisor: Patrizia GentiliDepartment staff: Fabrizio VeticaAntonio Di Sabato Publications 2‐(Hydroxyimino)aldehydes: Photo‐ and Physicochemical Properties of a Versatile Functional Group for Monomer DesignClick‐Connected 2‐(Hydroxyimino)aldehydes for the Design of UV‐Responsive Functional Molecules Collaborations National collaborations: Francesca D'Acunzo Theme and ERC Theme: Sustainable chemistryERC: PE4_12 Chemical reactions: mechanisms, dynamics, kinetics and catalytic reactionsPE5_13 Homogeneous catalysisPE5_17 Organic chemistry Traineeship offer Availability: one positionCourse of study (advised): Chemistry
