Beatrice Simonis

Dottorando in Modelli matematici per l'Ingegneria, elettromagnetismo, nanoscienze
Biography
Beatrice Simonis received her bachelor of science in chemistry in 2016 at the University of Rome “Tor Vergata” with a dissertation on “Metabolomic study of Trypanosome brucei: causes and effects of variability in biological response”. The internship was carried out at IRBM Science Park under the supervision of Prof. Daniel Oscar Cicero. In 2018 she obtained the master degree in Chemistry (specialization in the biological system) cum laude at the University of Rome “La Sapienza” discussing the thesis “Development of novel liposome formulations for the delivery of therapeutic substances to the central nervous systems” under the supervision of Dr. Francesca Ceccacci and prof. Luciano Galantini. In 2018 winner of the call "Thesis abroad" she carried out a part of the master's internship in the laboratory of the Department of Pharmacy of the University of Patras under the supervision of Prof. Sophia Antimisiaris. In the same year, she was the winner of the call “ Torno subito 2018 ” and spent a period of five months at the Institute of advance chemistry of Catalonia in the colloidal and interfacial chemistry group, focused on synthesis and characterization of gold nanorods and preparation and characterization of nano-emulsions and nanoparticles under the supervision of Dr. Carlos Rodríguez Abreu. Since 2019 she is a PhD student attending the doctorate in “Mathematical Models for Engineering, Electromagnetics and Nanosciences”, curriculum Materials Science, XXXV cycle under the supervision of Dr. Francesca Ceccacci and of prof. Luciano Galantini.
Research activity
Scientific area: 
Organic chemistry
Research activity: 
The topic of research is focused on the development of novel liposome formulations as drug delivery systems, tailored to load high amounts of therapeutics for the treatment of CNS diseases, cross the BBB and deliver the drug to the CNS. In order to cross BBB, liposomes will be functionalized with targeting moieties that should be able to trigger one among the different trans-cellular mechanisms involved in BBB crossing

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