Fabio Sciubba

titolare di contratto di lavoro autonomo

Biography

He attained the Degree in Chemistry with vote 110/110 cum laude (Università La Sapienza di Roma, 2005). He attained the PhD in Chemical Sciences (XXI cycle), grouping macromolecular biological (La Sapienza University of Rome, 2008). He attained the scholarship concerning the activity entitled " Metabolomica di frutta a guscio. Applicazione di metodiche avanzate di Risonanza Magnetica Nucleare " (Università La Sapienza di Roma, 2010). He was part-time fixed-term researcher (art. 1-comma14 of Law 230/2005) in CHIM / 07 Sector (Università Telematica Internazionale Uninettuno (UTIU), 2011). He was research fellow (category II) with the research project "Dalla qualità del prodotto alimentare al miglioramento dello stato di salute" CHIM / 02 Sector (Università La Sapienza di Roma, 2013). ). He was research fellow with the research project " FaReBio di Qualità Farmaci e Reti Biotecnologiche di Qualità” (CNR, Istituto di Cristallografia, 2014). He currently is research fellow with the research project “Valorizzazione dei prodotti agroalimentari del Fucino” (Università La Sapienza di Roma, 2015).

Curriculum:

CV Sciubba Europeo 3-19.pdf

Research activity

Scientific area:

Physical chemistry

Research activity:

Application of high resolution Nuclear Magnetic Resonance (HR-NMR) to: Characterization of macromolecular structures of biological origin such as proteins (lysozyme, albumin, beta-lactoglobulin) and cell membranes (caveolae); Structural analysis and motion parameter determination of nanoparticles (silver, gold, platinum and iron oxides); Structural analysis of organic and organometallic molecules with determination of chiral centers in diastereoisomer mixtures; Structural analysis of biocompatible polymers of natural and synthetic origin (carboxymethyl cellulose and derivatives, hyaluronic acid, alginic acid and derivatives, oligopeptides); Study of the interaction between macromolecules and small molecules of biological interest (acetyl-cholinesterase inhibitors, antioxidant molecules such as anthocyanins and ascorbic acid); Determination of the metabolic profile of cell and plant extracts (hepatocytes, fibroblasts, yeasts, leaves, roots, fresh and dried fruit) by NMR analysis and subsequent multivariate analysis. In all areas of research the most modern and efficient one- and two-dimensional NMR techniques are employed.